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Customer Case 1:
Wuhan University customer Published in Nature Medicine, IF=82.9
Title:An ALOX12–12-HETE–GPR31 signaling axis is a key mediator of hepatic ischemia–reperfusion injury
Methods: Adenovirus infection of primary hepatocytes
Figure2 ALOX12 directly promotes 12-HETE accumulation in hepatic IR injury
Customer Case 2:
Shanghai Jiao Tong University Affiliated Renji Hospital customer Published in CELL, IF=66.85
Title:Fusobacterium nucleatum Promotes Chemoresistance to Colorectal Cancer by Modulating Autophagy
Methods: MRFP-GFP-LC3 adenovirus vector infects HCT116 cells and HT29 cells
Figure2 F . Nucleatum promotes activation of cancer autophagy
Customer Case 3:
Southern Medical University customer Published in CELL, IF=66.85
Title:LECT2, a Ligand for Tie1, Plays a Crucial Role in Liver Fibrogenesis
Methods: Adenovirus is injected into mice through the tail vein (13 × Knock down Tie1, CD209a, and VEGFR2 for 108 pfu
Figure S.5 Tie1 is necessary for Lect2 to promote liver fibrosis
Customer Case 4:
First Affiliated Hospital of Guangxi Medical University customer Published in Molecular Cancer,IF=41.444
Title:Exosome-mediated miR-144-3p promotes ferroptosis to inhibit osteosarcoma proliferation, migration, and invasion through regulating ZEB1
Methods: The reporter plasmids ( wt, mut ) cloned with the 3'UTR of ZEB1 gene and miRNA were co-transfected to verify whether they were combined. Infect 143 B cells with lentivirus and adenovirus, overexpress or knock down ZEB1 gene, and screen stable expression cell lines.
Figure 3 The validation of exosome expression, function and downstream miR-144-3p/ZEB1 axis.
Customer Case 5:
Fuwai Hospital, Chinese Academy of Medical Sciences customer Published in Cell Discovery,IF=38.079
Title:Lineage-specific regulatory changes in hypertrophic cardiomyopathy unraveled by single-nucleus RNA-seq and spatial transcriptomics
Methods:Fibroblasts were infected with Adenovirus-AEBP1-GFP using a 1/2-volume method with MOI values of 300 or 400.
Figure 8 In vitro overexpression of AEBP1 attenuates the activation of human cardiac fibroblasts induced by TGFβ.
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